Glutamate Receptor Ionotropic, NMDA 2A (GRIN2A) (C-Term) antibody

Catalog No. ABIN361396

This Rabbit Polyclonal antibody specifically detects in ELISA, WB, IHC and IP. It exhibits reactivity toward Ratand has been mentioned in 1 publication.

Quick Overview for Glutamate Receptor Ionotropic, NMDA 2A (GRIN2A) (C-Term) antibody (ABIN361396)

Target: Glutamate Receptor Ionotropic, NMDA 2A (GRIN2A)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details

Binding Specificity: C-Term

Specificity: Specific for endogenous levels of the ~180 kDa NR2A subunit of the NMDA receptor. No reactivity towards the NR2B and NR2C subunits. Immunolabeling is blocked by pre-adsorption of antibody with the fusion protein used to generate the antibody.

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Characteristics: Our NMDA NR2A Subunit rabbit polyclonal primary antibody is produced in-house. It detects NMDA NR2A Subunit and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, IP.

Purification: Prepared from pooled rabbit serum by affinity purification using a column to which the fusion protein immunogen was coupled.

Immunogen: Fusion protein from the C-terminal region of the NR2A subunit of the rat NMDA receptor.

Isotype: IgG

Application Details

Application Notes:

Dilution Range: IP: 3 μL per 200 μg lysate

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Reconstitute in 50 μl phosphate buffered saline (PBS: 137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use. After reconstitution it is recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Expiry Date: 12 months

References

Morimura, Yasuda, Yamaguchi, Katayama, Hatayama, Tomioka, Odagawa, Kamiya, Iwayama, Maekawa, Nakamura, Matsuzaki, Tsujii, Yamada, Yoshikawa, Aruga: "Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice." in: Nature communications, Vol. 8, pp. 15800, (2018) (PubMed).

Target Details

Target: Glutamate Receptor Ionotropic, NMDA 2A (GRIN2A)

Alternative Name: EPND

Background:

Synonyms: EPND antibody, FESD antibody, GluN2A antibody, Glutamate [NMDA] receptor subunit epsilon-1 antibody, Glutamate receptor antibody, Glutamate receptor ionotropic N methyl D aspartate 2A antibody, GRIN 2A antibody, GRIN2A antibody, hNR2A antibody, LKS antibody, N methyl D aspartate receptor channel subunit epsilon 1 antibody, N Methyl D Aspartate Receptor Subtype 2A antibody, N methyl D aspartate receptor subunit 2A antibody, N-methyl D-aspartate receptor subtype 2A antibody, NMDA receptor subtype 2A antibody, NMDAR 2A antibody, NMDAR2A antibody, NMDE1_HUMAN antibody, NR2A antibody, OTTHUMP00000160135 antibody, OTTHUMP00000174531 antibody

Description Logic: Our NMDA NR2A Subunit rabbit polyclonal primary antibody is produced . It detects NMDA NR2A Subunit and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, IP.

Gene Name Alternatives: GRIN2A

Molecular Weight: 180 kDa

Gene ID: 24409

UniProt: Q00959